Sermorelin

Investigated uses

• No adequately documented human investigated use for the exact catalog identity/formulation was identified; any vendor-promoted goals were excluded from evidence grading.

Mechanism and hypotheses

• Sermorelin is GHRH(1-29) amide and stimulates pituitary growth-hormone secretion.
• Hypothesized: Current anti-aging and body-composition uses are not supported by a current FDA-approved sermorelin product identified in this review.

Human evidence

• No qualifying controlled human efficacy study for the exact catalog identity/formulation was identified in this review. Limitations: This is a bounded search conclusion, not proof that no report exists; identity, language and indexing limitations may apply.

Safety highlights

• Unknown or insufficiently characterized for the exact catalog product.
• Identity, purity, sterility, endotoxin, aggregation, immunogenicity, concentration and route-specific risks are not adequately characterized.

Regulatory context

No FDA-approved product matching the exact catalog presentation was identified in this review.