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#49Neurological, Sexual & Related

Kisspeptin-10

KISS1 receptor agonist decapeptide

Evidence: human RCTReviewed 2026-07-25

Investigated uses

  • No adequately documented human investigated use for the exact catalog identity/formulation was identified; any vendor-promoted goals were excluded from evidence grading.

Mechanism and hypotheses

  • Kisspeptin-10 activates KISS1R and can stimulate hypothalamic–pituitary–gonadal signaling in controlled human studies.
  • Hypothesized: Fertility or endocrine use outside protocol-defined formulations remains investigational.

Human evidence

  • No qualifying controlled human efficacy study for the exact catalog identity/formulation was identified in this review. Limitations: This is a bounded search conclusion, not proof that no report exists; identity, language and indexing limitations may apply.

Safety highlights

  • Unknown or insufficiently characterized for the exact catalog product.
  • Identity, purity, sterility, endotoxin, aggregation, immunogenicity, concentration and route-specific risks are not adequately characterized.

Regulatory context

No FDA-approved product matching the exact catalog presentation was identified in this review.

Sources used for this entry