#49Neurological, Sexual & Related
Kisspeptin-10
KISS1 receptor agonist decapeptide
Evidence: human RCTReviewed 2026-07-25
Investigated uses
- No adequately documented human investigated use for the exact catalog identity/formulation was identified; any vendor-promoted goals were excluded from evidence grading.
Mechanism and hypotheses
- Kisspeptin-10 activates KISS1R and can stimulate hypothalamic–pituitary–gonadal signaling in controlled human studies.
- Hypothesized: Fertility or endocrine use outside protocol-defined formulations remains investigational.
Human evidence
- No qualifying controlled human efficacy study for the exact catalog identity/formulation was identified in this review. Limitations: This is a bounded search conclusion, not proof that no report exists; identity, language and indexing limitations may apply.
Safety highlights
- Unknown or insufficiently characterized for the exact catalog product.
- Identity, purity, sterility, endotoxin, aggregation, immunogenicity, concentration and route-specific risks are not adequately characterized.
Regulatory context
No FDA-approved product matching the exact catalog presentation was identified in this review.
Sources used for this entry
- Kisspeptin-10 human trial search — PubMed
- PubMed search: Kisspeptin-10 — PubMed
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks — U.S. Food and Drug Administration
- Drugs@FDA database — U.S. Food and Drug Administration
- EMA medicines search — European Medicines Agency