#34Growth Hormone & Body Composition
GHRP-2 acetate
ghrelin/growth-hormone-secretagogue receptor agonist
Evidence: other human studyReviewed 2026-07-25
Investigated uses
- No adequately documented human investigated use for the exact catalog identity/formulation was identified; any vendor-promoted goals were excluded from evidence grading.
Mechanism and hypotheses
- GHRP-2 is a ghrelin/growth-hormone-secretagogue receptor agonist that can increase GH release in humans.
- Hypothesized: Anti-aging, recovery and body-composition benefits are not established approved outcomes.
Human evidence
- No qualifying controlled human efficacy study for the exact catalog identity/formulation was identified in this review. Limitations: This is a bounded search conclusion, not proof that no report exists; identity, language and indexing limitations may apply.
Safety highlights
- Endocrine/metabolic effects and immunogenicity are concerns.
- FDA notes serious adverse events reported in studies, including increased insulin requirements, infection, pancreatitis and deaths in critically ill subjects; causality was not established.
Regulatory context
No FDA-approved GHRP-2 drug was identified; FDA lists it among substances presenting significant compounding safety concerns.
Sources used for this entry
- Growth hormone-releasing peptide human trial search — PubMed
- PubMed search: GHRP-2 acetate — PubMed
- Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks — U.S. Food and Drug Administration
- Drugs@FDA database — U.S. Food and Drug Administration
- EMA medicines search — European Medicines Agency