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#34Growth Hormone & Body Composition

GHRP-2 acetate

ghrelin/growth-hormone-secretagogue receptor agonist

Evidence: other human studyReviewed 2026-07-25

Investigated uses

  • No adequately documented human investigated use for the exact catalog identity/formulation was identified; any vendor-promoted goals were excluded from evidence grading.

Mechanism and hypotheses

  • GHRP-2 is a ghrelin/growth-hormone-secretagogue receptor agonist that can increase GH release in humans.
  • Hypothesized: Anti-aging, recovery and body-composition benefits are not established approved outcomes.

Human evidence

  • No qualifying controlled human efficacy study for the exact catalog identity/formulation was identified in this review. Limitations: This is a bounded search conclusion, not proof that no report exists; identity, language and indexing limitations may apply.

Safety highlights

  • Endocrine/metabolic effects and immunogenicity are concerns.
  • FDA notes serious adverse events reported in studies, including increased insulin requirements, infection, pancreatitis and deaths in critically ill subjects; causality was not established.

Regulatory context

No FDA-approved GHRP-2 drug was identified; FDA lists it among substances presenting significant compounding safety concerns.

Sources used for this entry